Use of Amitriptyline almost doubled symptom improvement in IBS

Use of Amitriptyline almost doubled symptom improvement in IBS

GLASGOW, UK Amitriptyline, titrated at low doses, outperformed placebo as a second-line treatment for irritable bowel syndrome (IBS) across multiple outcomes in what researchers called a trial Largest randomized controlled trial (RCT) of tricyclic antidepressants in this condition. According to the investigators of the Low-Dose and Titrated Amitriptyline for Irritable Bowel Syndrome as Second-Line Treatment … Read more

The common antidepressant amitriptyline also reduces the painful symptoms of irritable bowel syndrome

The common antidepressant amitriptyline also reduces the painful symptoms of irritable bowel syndrome

LEEDS, UK — Antidepressants may also reduce symptoms of irritable bowel syndrome (IBS) in patients under the care of a general practitioner (GP). British researchers conducted the study in primary care settings where GPs prescribed amitriptyline – whose trade names include Elavil and Vanatrip. Patients adjusted their dose based on the severity of their symptoms … Read more