Use of Amitriptyline almost doubled symptom improvement in IBS
GLASGOW, UK Amitriptyline, titrated at low doses, outperformed placebo as a second-line treatment for irritable bowel syndrome (IBS) across multiple outcomes in what researchers called a trial Largest randomized controlled trial (RCT) of tricyclic antidepressants in this condition. According to the investigators of the Low-Dose and Titrated Amitriptyline for Irritable Bowel Syndrome as Second-Line Treatment … Read more